Monday, April 30, 2007

Metformin slows antipsychotic drug weight gain

Metformin safely and effectively abrogates weight gain and adverse metabolic changes that occur with atypical antipsychotic drug therapy in children, a new study shows.

"Weight gain was shown recently to be the most important factor leading to noncompliance with these very effective medications," study leader Dr. David J. Klein, from Cincinnati Children's Hospital Medical Center, Ohio, told Reuters Health.

Atypical antipsychotics generally have fewer side effects than some of the older antipsychotic drugs. Some of the drugs in this newer class of antipsychotics commonly prescribed include risperidone, sold as Risperdal; quetiapine, sold as Seroquel; and olanzapine, sold as Zyprexa.

READ MORE @ Reuters

Primary text: American Journal of Psychiatry, December 2006