Antipsychotic medications have different effects depending on the patient's specific metabolism and ethnicity, according to a post-hoc analysis of a randomized trial that compared aripiprazole and olanzapine reported here at the 161st Annual Meeting of the American Psychiatric Associations (APA).
The study compared the metabolic and racial and/or ethnic effects of 2 antipsychotic medications -- olanzapine and aripiprazole -- that are both approved by the US Food and Drug Administration for treatment of schizophrenia.
In the 26-week, double-blind, randomized, controlled trial, the effects of aripiprazole and olanzapine were compared in patients who had been grouped according to their ethnicity -- "White/Other" (n = 67); "Black" (n = 86); "Hispanic" (n = 51)
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