A pioneer in psychiatry

Dr. Frank J. Ayd Jr., a Baltimore psychiatrist who pioneered the field of psychopharmacology when he began treating schizophrenics with Thorazine in the early 1950s, died in his sleep Monday at Lorien Mays Chapel Health Care Center. He was 87.

At a time when the psychiatric establishment rejected the notion that mental illness was rooted in biology, Dr. Ayd championed the use of medications to adjust brain chemistry and, in so doing, relieve a patient's suffering.

"He was a biological psychiatrist, one of the important kinds of people who in spite of - and against - the establishment had the guts to stand up and really do things," said Dr. Thomas Ban, an emeritus professor of psychiatry at Vanderbilt University in Nashville, Tenn.

"Many people claim pioneering, but he really was. He entered the field when the whole thing started."

Dr. Philip G. Janicak, a Chicago psychiatrist and editor of International Drug Therapy Newsletter, said, "Dr. Ayd was one of the founding fathers of modern psychiatry. He changed the direction of psychiatry."

Dr. Janicak added: "He saw the potential value of medications to treat serious psychiatric disorders."

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Big Headache for Big Pharma

For pharmaceutical giant Eli Lilly, death and injury are just a cost of doing business. When Zyprexa, Lilly’s drug to treat schizophrenia and bipolar disorder, hit the marketplace in 1996, it was hailed as an “atypical” – a “safe, gentle psychotropic,” more effective than older drugs like Thorazine and Trilafon, without the dangerous side effects. Sales skyrocketed. The hype soon gave way to reality, as Lilly faced waves of lawsuits by patients suffering from diabetes, massive weight gain, pancreatitis and cardiac problems. Lilly responded with the cozy arrangement that worked with Prozac, another blockbuster plagued with problems: quietly settle suits out of court, with proceedings sealed and secret under a gag order. Anything embarrassing – or illegal – that Lilly is doing behind closed doors would remain hidden from public view.

By - Will Hall co-founder of the Freedom Center, and a member of the Icarus Project.

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Antipsychotic Medicine Inspires Tuberculosis Drug

The antipsychotic medication chlorpromazine (Thorazine) can be used to treat tuberculosis, but it causes terrible side effects. Scientists at SRI International are using this knowledge as a starting point to develop a new tuberculosis drug. Their challenge is to find a chemical that kills Mycobacterium tuberculosis, the bacteria that causes tuberculosis, without causing restlessness and uncontrollable jitters that are brought on by the antipsychotic medication.

READ MORE @ Wired News