Nursing home patients who take antipsychotic drugs are 60 percent more likely to develop pneumonia in the short term than those who don't take the drugs, a new study shows.
The risk is greatest during the first week after patients start taking the medications and gradually decreases, say Dutch researchers.
"The risk of developing pneumonia is not associated with long-term use, but is the highest shortly after starting the drug," said study authors Dr. Rob van Marum and Dr. Wilma Knol. They warned that "all antipsychotic drugs may be associated with pneumonia in elderly patients."
This is the first study to show an association between pneumonia risk and the use of antipsychotic drugs, which are frequently used to treat psychosis and behavioral problems in elderly patients with dementia and delirium.
The study was published in the current issue of theJournal of the American Geriatrics Society.
READ MORE @ WASHINGTON POST
Showing posts with label pneumonia. Show all posts
Showing posts with label pneumonia. Show all posts
Wednesday, April 30, 2008
Sunday, April 27, 2008
Antipsychotic drugs up pneumonia risk in elderly
Older patients given antipsychotic drugs are at increased risk of pneumonia, particularly during the first week after starting treatment, Dutch researchers report. Thirty days after treatment begins, however, the risk is no longer apparent.
Elderly people are often prescribed antipsychotic drugs, Dr. Rob J. van Marum, at University Medical Center in Utrecht, and colleagues point out in a report in the Journal of the American Geriatrics Society. Usually treatment is related to controlling the effects of dementia, but not always.
In fact, studies have shown that up to 40 percent of nursing home residents are treated with the drugs, and in half of those cases the treatment is "inappropriate."
To look at the risk of pneumonia with antipsychotic drugs, the researchers studied information from community pharmacies and the hospital records of 22,944 patients aged 65 or older who received a prescription for an antipsychotic at some point between 1985 and 2003.
After taking into account factors such as age, other medications, and other illnesses, the investigators found that the likelihood of being hospitalized for pneumonia was 60 percent higher for subjects who were currently on an antipsychotic medication than for those who were weren't.
READ MORE @ REUTERS
Elderly people are often prescribed antipsychotic drugs, Dr. Rob J. van Marum, at University Medical Center in Utrecht, and colleagues point out in a report in the Journal of the American Geriatrics Society. Usually treatment is related to controlling the effects of dementia, but not always.
In fact, studies have shown that up to 40 percent of nursing home residents are treated with the drugs, and in half of those cases the treatment is "inappropriate."
To look at the risk of pneumonia with antipsychotic drugs, the researchers studied information from community pharmacies and the hospital records of 22,944 patients aged 65 or older who received a prescription for an antipsychotic at some point between 1985 and 2003.
After taking into account factors such as age, other medications, and other illnesses, the investigators found that the likelihood of being hospitalized for pneumonia was 60 percent higher for subjects who were currently on an antipsychotic medication than for those who were weren't.
READ MORE @ REUTERS
Friday, April 18, 2008
Antipsychotic Drugs Increase Risk Of Developing Pneumonia In Elderly, Study Suggests
Elderly patients who use antipsychotic drugs have a 60 percent increased risk of developing pneumonia compared to non-users. This risk is highest in the first week following prescription and decreases gradually thereafter. Antipsychotic drugs are frequently used in elderly patients for the treatment of psychosis and behavioral problems associated with dementia and delirium. This study is the first to show that the development of pneumonia is associated with antipsychotic drug use.
“The risk of developing pneumonia is not associated with long-term use, but is the highest shortly after starting the drug,” say Drs. Rob van Marum and Wilma Knol, authors of the study. They caution that “all antipsychotic drugs may be associated with pneumonia in elderly patients.”
READ MORE @ SCIENCE DAILY
“The risk of developing pneumonia is not associated with long-term use, but is the highest shortly after starting the drug,” say Drs. Rob van Marum and Wilma Knol, authors of the study. They caution that “all antipsychotic drugs may be associated with pneumonia in elderly patients.”
READ MORE @ SCIENCE DAILY
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