Antidepressants are an effective treatment for patients with irritable bowel syndrome (IBS), according to results presented here at the American College of Gastroenterology (ACG) 73rd Annual Scientific Meeting.
Alexander Ford, MD, McMaster University Medical Centre, Hamilton, Ontario, reported the results of a systematic review in a poster session here on October 5.
"I think the most exciting finding [of our study] is that this hasn't been shown before. It's probably the first time that a systematic review and meta-analysis has shown that antidepressants are a benefit in treating irritable bowel syndrome," said Dr. Ford.
"Previous meta-analyses have not demonstrated such an effect for a number of reasons. Obviously, there's more data now but also [researchers] haven't quite looked at all of the eligible studies for various reasons. I think one of [the studies] should have been able to demonstrate this benefit 3 or 4 years ago, but just didn't manage to."
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